Newcastle University is a centre of excellence in clinical and translational research, and has close link with the Newcastle upon Tyne Hospitals NHS Foundation Trust. The Faculty of Medical Sciences has achieved the highest grades of 5 and 5* by national and international assessors in the most recent RAE 2001. The purpose-built £4.5 million Clinical Research Facility, a joint venture of the university and the Newcastle Hospitals NHS Foundation Trust, is equipped with state-of the-art facilities and is well-placed to promote bench-to bedside translational research.

In our department, we have assessed to several well characterised patient cohorts including systemic lupus erythematosus (SLE), psoriatic arthritis and spondylo-arthropathy, early rheumatoid arthritis, sjogren’s syndrome as well as autoimmune polyendocrinopathy candidasis ectodermal dystrophy (APECED), a condition with organ-specific autoimmunity and is linked to targeted mutation of the AIRE gene. Successful applicant will be expected to develop research into the role of regulatory T cells in mediating both systemic and organ-specific autoimmune processes and to establish projects into the role of cellular interaction of regulatory T cells with parenchymal and other non-immune cells in end-organ tissue damage. This post is for a duration of 1 year. Opportunity to develop related project that match the expertise of the successful applicant will also be encouraged.

A PhD in relevant subject is required. Experience in cellular and molecular immunology and will be an advantage but not essential. Starting salary is £24,402 – 31,840 p.a. depending on skills and experience.

Informal enquiries should be made to Dr. Fai Ng, Tel: +44-(191)-2228125 or e-mail: Wan-fai.Ng@ncl.ac.uk.