The project will use engineered nano-structures to host ovarian or uterine cells that facilitate the “self-assembly” of ovarian follicles and uterine endometrium. The impact of the shape and form of the nano-structures will be evaluated by measuring mechanical forces at the cellular level and testing biological function.  The optimal 3D models will be used to test the effect of infection on endocrine and immune function.

The project is at the interface between medicine, biology and engineering. The student will be exposed to three rich research environments: London, Swansea and Pfizer working in well-funded groups. This mix of environments provides access to some of the most advanced technology including atomic force and confocal microscopy and nano-engineering facilities as well as biological laboratories experienced in the cell and molecular techniques required. We are also collaborating with Prof David Albertini, Kansas, and Prof Robert Brown, UCL, who have considerable experience in the field.

We are seeking an enthusiastic and motivated individual with a first or upper second class science degree. The studentship will provide fees at UK/EU level and a PhD stipend tenable from October 2007.

Training